NR3C1 polyclonal (Center), anti-human, mouse
€0.00
In stock
SKU
AC-AP5468c
Catalog Number: AC-AP5468c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB26744
Applications: IF, IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB26744
Applications: IF, IHC-P, WB
Datasheet
Request Information
Background:
NR3C1 is a receptor forglucocorticoids that can act as both a transcription factor and asa regulator of other transcription factors. This protein can alsobe found in heteromeric cytoplasmic complexes along with heat shockfactors and immunophilins. The protein is typically found in thecytoplasm until it binds a ligand, which induces transport into thenucleus. Mutations in this gene are a cause of glucocorticoidresistance, or cortisol, resistance. Alternate splicing, the use ofat least three different promoters, and alternate translationinitiation sites result in several transcript variants encoding thesame protein or different isoforms, but the full-length nature ofsome variants has not been determined.
Other Names:
Glucocorticoid receptor, GR, Nuclear receptor subfamily 3 group C member 1, NR3C1, GRL
Target/Specificity:
This NR3C1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-262 amino acids from the Central region of human NR3C1.
Antigen Region:
236-262
Antigen Type: Synthetic Peptide
Gene Name: NR3C1 (HGNC:7978)
Gene ID: 2908
Primary Accession: P04150
NCBI Accession: NP_000167.1;NP_001018084.1;NP_001018085.1;NP_001018086.1;NP_001018087.1;NP_001018661.1;NP_001019265.1;NP_001191187.1;NP_001191188.1;NP_001191189.1;NP_001191190.1;NP_001191191.1;NP_001191192.1;NP_00119
Other Accession: P59667; NP_000167.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
NR3C1 is a receptor forglucocorticoids that can act as both a transcription factor and asa regulator of other transcription factors. This protein can alsobe found in heteromeric cytoplasmic complexes along with heat shockfactors and immunophilins. The protein is typically found in thecytoplasm until it binds a ligand, which induces transport into thenucleus. Mutations in this gene are a cause of glucocorticoidresistance, or cortisol, resistance. Alternate splicing, the use ofat least three different promoters, and alternate translationinitiation sites result in several transcript variants encoding thesame protein or different isoforms, but the full-length nature ofsome variants has not been determined.
Other Names:
Glucocorticoid receptor, GR, Nuclear receptor subfamily 3 group C member 1, NR3C1, GRL
Target/Specificity:
This NR3C1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-262 amino acids from the Central region of human NR3C1.
Antigen Region:
236-262
Antigen Type: Synthetic Peptide
Gene Name: NR3C1 (HGNC:7978)
Gene ID: 2908
Primary Accession: P04150
NCBI Accession: NP_000167.1;NP_001018084.1;NP_001018085.1;NP_001018086.1;NP_001018087.1;NP_001018661.1;NP_001019265.1;NP_001191187.1;NP_001191188.1;NP_001191189.1;NP_001191190.1;NP_001191191.1;NP_001191192.1;NP_00119
Other Accession: P59667; NP_000167.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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