NR3C2 polyclonal (Center), anti-human
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In stock
SKU
AC-AP17202c
Catalog Number: AC-AP17202c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36767
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36767
Applications: WB
Datasheet
Request Information
Background:
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.
Other Names:
Mineralocorticoid receptor, MR, Nuclear receptor subfamily 3 group C member 2, NR3C2, MCR, MLR
Target/Specificity:
This NR3C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 654-683 amino acids from the Central region of human NR3C2.
Antigen Region:
654-683
Antigen Type: Synthetic Peptide
Gene Name: NR3C2
Gene ID: 4306
Primary Accession: P08235
NCBI Accession: NP_000892.2;NP_001159576.1
Other Accession: Q91573; P22199; Q8VII8; NP_000892.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.
Other Names:
Mineralocorticoid receptor, MR, Nuclear receptor subfamily 3 group C member 2, NR3C2, MCR, MLR
Target/Specificity:
This NR3C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 654-683 amino acids from the Central region of human NR3C2.
Antigen Region:
654-683
Antigen Type: Synthetic Peptide
Gene Name: NR3C2
Gene ID: 4306
Primary Accession: P08235
NCBI Accession: NP_000892.2;NP_001159576.1
Other Accession: Q91573; P22199; Q8VII8; NP_000892.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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