NRAS Polyclonal Antibody

Background:
This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. 

Research Area: Cancer, Signal Transduction

Synonyms:
ALPS4, AV095280, GTPase NRas, HRAS1, N ras, N ras protein part 4, Neuroblastoma RAS viral (v ras) oncogene homolog, NRAS, NRAS1, NS6, OTTHUMP00000013879, OTTMUSP00000023521, RASN, Transforming protein N Ras, Transforming protein N-Ras, v ras neuroblastoma RAS viral oncogene homolog

Immunogen: Recombinant Human GTPase NRas protein

Swissprot: P01111

Purification Method: Affinity purification

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Concentration: 2 mg/mL
Dilution: IHC 1:100-1:400

Storage:
Store at -20°C. Avoid freeze / thaw cycles.