NRF1 polyclonal (Center), anti-human

NRF1 polyclonal (Center), anti-human

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In stock
SKU
AC-AP14535c
Catalog Number: AC-AP14535c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34424
Applications: WB
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Background:
This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for 'nuclear factor (erythroid-derived 2)-like 1' which has an official symbol of NFE2L1.

Other Names:
Nuclear respiratory factor 1, NRF-1, Alpha palindromic-binding protein, Alpha-pal, NRF1

Target/Specificity:
This NRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-255 amino acids from the Central region of human NRF1.

Antigen Region:
226-255

Antigen Type: Synthetic Peptide

Gene Name: NRF1
Gene ID: 4899
Primary Accession: Q16656
NCBI Accession: NP_001035199.1;NP_005002.3
Other Accession: Q9WU00; Q90X44; NP_005002.3; NP_001035199.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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