NRG1 polyclonal, anti-human

Quantity: 100 µg

Background:
The protein encoded by this gene is a membrane glycoprotein that that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

Description:
Rabbit IgG polyclonal antibody for Pro-neuregulin-1, membrane-bound isoform (NRG1) detection. Tested with WB in Human.

Synonyms:
Acetylcholine receptor inducing activity antibody, Acetylcholine receptor-inducing activity antibody, Acetylcholine receptor-inducing activity, CHICK, homolog of antibody, ARIA antibody, Breast cancer cell differentiation factor p45 antibody, ERBB2 p185 activator antibody, GGF 2 antibody, GGF antibody, GGF2 antibody, Glial growth factor antibody, Heregulin alpha antibody, Heregulin antibody, heregulin, alpha (45kD, ERBB2 p185-activator) antibody, HGL antibody, HRG 1 antibody, HRG antibody, HRG1 antibody, HRGA antibody, MST131 antibody, NDF antibody, Neu differentiation factor antibody, Neuregulin 1 antibody, neuregulin 1 type IV beta 1a antibody, neuregulin 1 type IV beta 3 antibody, Neuregulin-1 antibody, Neuregulin1 antibody, NRG 1 antibody, nrg1 antibody, NRG1-IT2 antibody, NRG1_HUMAN antibody, OTTHUMP00000225398 antibody, OTTHUMP00000225419 antibody, OTTHUMP00000225420 antibody, OTTHUMP00000225421 antibody, OTTHUMP00000225422 antibody, OTTHUMP00000225477 antibody, OTTHUMP00000225545 antibody, OTTHUMP00000230603 antibody, OTTHUMP00000230605 antibody, Pro neuregulin 1 antibody, Pro NRG1 antibody, pro-neuregulin-1, membrane-bound isoform antibody, Pro-NRG1 antibody, Proneuregulin 1 antibody, ProNRG1 antibody, Sensory and motor neuron derived factor antibody, Sensory and motor neuron-derived factor antibody, SMDF antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human NRG1 recombinant protein (Position: S2-K241). Human NRG1 shares 94% amino acid (aa) sequence identity with rat NRG1.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.