NRG1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
NRG1(Neuregulin 1), also known as ARIA, NDF or HRGA, is a protein that in humans is encoded by the NRG1 gene. NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. By in situ hybridization of a tritium-labeled probe to human metaphase spreads, Orr-Urtreger et al.(1993) localized the NDF gene to 8p21-p12. In mouse embryos 14.5 days postcoitum, Orr-Urtreger et al.(1993) found that NDF expression is confined predominantly to the central and peripheral nervous systems, including the neuroepithelium that lines the lateral ventricles of the brain, the ventral horn of the spinal cord, and the intestinal as well as dorsal root ganglia.

Description:
Rabbit IgG polyclonal antibody for Pro-neuregulin-1, membrane-bound isoform (NRG1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human, Mouse, Rat.

Synonyms:
Acetylcholine receptor inducing activity antibody, Acetylcholine receptor-inducing activity antibody, ARIA antibody, Breast cancer cell differentiation factor p45 antibody, GGF antibody, GGF2 antibody, Glial growth factor antibody, heregulin antibody, heregulin, alpha(45kD, ERBB2 p185-activator) antibody, HGL antibody, HRG antibody, HRG1 antibody, HRGA antibody, MST131 antibody, NDF antibody, Neu differentiation factor antibody, Neuregulin 1 antibody, neuregulin 1 type IV beta 1a antibody, neuregulin 1 type IV beta 3 antibody, Neuregulin-1 antibody, NRG 1 antibody, nrg1 antibody, NRG1_HUMAN antibody, OTTHUMP00000225398 antibody, OTTHUMP00000225419 antibody, OTTHUMP00000225420 antibody, OTTHUMP00000225421 antibody, OTTHUMP00000225422 antibody, OTTHUMP00000225477 antibody, OTTHUMP00000225545 antibody, OTTHUMP00000230603 antibody, OTTHUMP00000230605 antibody, Pro-NRG1 antibody, ProNRG1 antibody, Sensory and motor neuron-derived factor antibody, SMDF antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human NRG1(617-636aa RFSTQEEIQARLSSVIANQD), different from the related rat and mouse sequences by one amino acids.A synthetic peptide corresponding to a sequence at the C-terminus of human NRG1(617-636aa RFSTQEEIQARLSSVIANQD), different from the related rat and mouse sequences by one amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P, IHC-F, ICC

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.