NRG1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6037
Background:
Neuregulin-1 gene, NRG1, encodes numerous splice variants with differing transcription initiation sites. Neuregulin-1 includes a range of isoforms with varying glycosylation, regulation of expression and function. Neuregulin-1 splice variants each bear an EGF-like domain, though otherwise have unique domain structures, differing functions and discrete tissue distribution. Six types of Neuregulin-1 isoform groups have been defined based on their structural features. Three types are most often described, type I (ARIA, NDF or HRG), type II (GGF) and type III (SMDF). Neuregulin-1 has been linked to schizophrenia and has diverse neural functions. Neuregulin-1 affects cell migration, the differentiation of neural crest and Schwann cells, and acts to upregulate the expression of acetylcholine receptors at muscle fibers during the formation of neuromuscular junctions.
Alternative Name:
Acetylcholine receptor inducing activity, Acetylcholine receptor-inducing activity, ARIA, Breast cancer cell differentiation factor p45, ERBB2 p185 activator, GGF 2, GGF, GGF2, Glial growth factor, Heregulin alpha, Heregulin, heregulin, alpha (45, ERBB2 p185-activator), HGL, HRG 1, HRG, HRG1, HRGA, MST131, NDF, Neu differentiation factor, Neuregulin 1, neuregulin 1 type IV beta 1a, neuregulin 1 type IV beta 3, Neuregulin-1, Neuregulin1, NRG 1, nrg1, NRG1, OTTHU
Application Dilution: WB: 1:500~1:2000
Specificity: NRG1 polyclonal antibody detects endogenous levels of NRG1 protein.
Immunogen:
Recombinant full length Human NRG1.
MW: ~ 30,50,70 kDa
Swis Prot.: Q02297
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Neuregulin-1 gene, NRG1, encodes numerous splice variants with differing transcription initiation sites. Neuregulin-1 includes a range of isoforms with varying glycosylation, regulation of expression and function. Neuregulin-1 splice variants each bear an EGF-like domain, though otherwise have unique domain structures, differing functions and discrete tissue distribution. Six types of Neuregulin-1 isoform groups have been defined based on their structural features. Three types are most often described, type I (ARIA, NDF or HRG), type II (GGF) and type III (SMDF). Neuregulin-1 has been linked to schizophrenia and has diverse neural functions. Neuregulin-1 affects cell migration, the differentiation of neural crest and Schwann cells, and acts to upregulate the expression of acetylcholine receptors at muscle fibers during the formation of neuromuscular junctions.
Alternative Name:
Acetylcholine receptor inducing activity, Acetylcholine receptor-inducing activity, ARIA, Breast cancer cell differentiation factor p45, ERBB2 p185 activator, GGF 2, GGF, GGF2, Glial growth factor, Heregulin alpha, Heregulin, heregulin, alpha (45, ERBB2 p185-activator), HGL, HRG 1, HRG, HRG1, HRGA, MST131, NDF, Neu differentiation factor, Neuregulin 1, neuregulin 1 type IV beta 1a, neuregulin 1 type IV beta 3, Neuregulin-1, Neuregulin1, NRG 1, nrg1, NRG1, OTTHU
Application Dilution: WB: 1:500~1:2000
Specificity: NRG1 polyclonal antibody detects endogenous levels of NRG1 protein.
Immunogen:
Recombinant full length Human NRG1.
MW: ~ 30,50,70 kDa
Swis Prot.: Q02297
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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