NRG2 Polyclonal Antibody

Background:
This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described.

Research Area: Neuroscience, Signal Transduction

Synonyms:
Divergent of neuregulin 1, Divergent of neuregulin-1, Don 1, DON-1, Neural- and thymus-derived activator for ERBB kinases, Neuregulin 2, Neuregulin-2, NRG-2, Nrg2, NRG2, NTAK, Pro NRG2, Pro-NRG2

Immunogen: Synthetic peptide of human NRG2

Swissprot: O14511
Gene Accession: NP001171864

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.