NRG3 polyclonal, anti-human, mouse

Background:
This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4.

Synonyms: HRG3, pro-NRG3

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human NRG3

Gene Symbol: NRG3

Gene ID: 10718

Swiss prot: P56975

Calculated MW: 78kDa

Recommended dilution:
WB 1:200-1000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.