NSE/Enolase polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7180
Background:
Enolase is a glycolytic enzyme catalyzing the reaction pathway between 2 phospho glycerate and phosphoenol pyruvate. In mammals, enolase molecules are dimers composed of three distinct subunits (alpha, beta and gamma). The alpha subunit is expressed in most tissues and the beta subunit only in muscle. The gamma subunit is expressed primarily in neurons, in normal and in neoplastic neuroendocrine cells. NSE (neuron specific enolase) is found in elevated concentrations in plasma in certain neoplasias. These include pediatric euroblastoma and small cell lung cancer. Coexpression of NSE and chromogranin A is common in neuroendocrine neoplasms
Alternative Name:
Gamma-enolase, Gamma-enolase, Enolase 2, Neural enolase, Neural enolase, NSE, ENO2
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: NSE/Enolase polyclonal antibody detects endogenous levels of NSE/Enolase protein.
Immunogen:
Recombinant full length Human NSE/Enolase.
MW: ~ 47 kDa
Swis Prot.: P09104
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Enolase is a glycolytic enzyme catalyzing the reaction pathway between 2 phospho glycerate and phosphoenol pyruvate. In mammals, enolase molecules are dimers composed of three distinct subunits (alpha, beta and gamma). The alpha subunit is expressed in most tissues and the beta subunit only in muscle. The gamma subunit is expressed primarily in neurons, in normal and in neoplastic neuroendocrine cells. NSE (neuron specific enolase) is found in elevated concentrations in plasma in certain neoplasias. These include pediatric euroblastoma and small cell lung cancer. Coexpression of NSE and chromogranin A is common in neuroendocrine neoplasms
Alternative Name:
Gamma-enolase, Gamma-enolase, Enolase 2, Neural enolase, Neural enolase, NSE, ENO2
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: NSE/Enolase polyclonal antibody detects endogenous levels of NSE/Enolase protein.
Immunogen:
Recombinant full length Human NSE/Enolase.
MW: ~ 47 kDa
Swis Prot.: P09104
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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