NSMAF Antibody (N-term) Blocking peptide

Background:
This gene encodes a WD-repeat protein that binds thecytoplasmic sphingomyelinase activation domain of the 55kD tumornecrosis factor receptor. This protein is required for TNF-mediatedactivation of neutral sphingomyelinase and may play a role inregulating TNF-induced cellular responses such as inflammation.Alternative splicing results in multiple transcript variants.

Other Names:
Protein FAN, Factor associated with neutral sphingomyelinase activation, Factor associated with N-SMase activation, NSMAF, FAN

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13585a was selected from the N-term region of NSMAF. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: NSMAF

Gene ID: 8439
Primary Accession: Q92636
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.