NSMCE4A C-terminal region polyclonal, anti-human, mouse, rat, rabbit, horse, bovine, guinea pig, dog
€474.00
In stock
SKU
AC-AI15899
Catalog Number: AC-AI15899
Size: 50 µg
Isotype: rabbit IgG
Applications: WB, IF
Datasheet
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Size: 50 µg
Isotype: rabbit IgG
Applications: WB, IF
Datasheet
Request Information
Background:
Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT- associated PML bodies (APBs). Is involved in positive regulation of response to DNA damage stimulus.
Other Names:
Non-structural maintenance of chromosomes element 4 homolog A, NS4EA, Non-SMC element 4 homolog A, NSMCE4A, C10orf86
Immunogen:
The immunogen for Anti-NSMCE4A antibody is: synthetic peptide directed towards the C-terminal region of Human NSMCE4A
Gene Name:
NSMCE4A
Gene Name:
54780
NCBI Accession:
NP_060085
Primary Accession: Q9NXX6
Other Accession: NM_017615;NP_060085
Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT- associated PML bodies (APBs). Is involved in positive regulation of response to DNA damage stimulus.
Other Names:
Non-structural maintenance of chromosomes element 4 homolog A, NS4EA, Non-SMC element 4 homolog A, NSMCE4A, C10orf86
Immunogen:
The immunogen for Anti-NSMCE4A antibody is: synthetic peptide directed towards the C-terminal region of Human NSMCE4A
Gene Name:
NSMCE4A
Gene Name:
54780
NCBI Accession:
NP_060085
Primary Accession: Q9NXX6
Other Accession: NM_017615;NP_060085
Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
| Is Featured? | No |
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