NSUN2 Polyclonal Antibody

Background:
This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
NSUN2, MISU, MRT5, SAKI, TRM4

Immunogen: Recombinant fusion protein of human NSUN2 (NP_060225.4).

Swissprot: Q08J23
Gene ID: 54888

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.