NSUN6 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS8774
Background:
The nucleolus consists of a number of specific proteins that play a critical role in the assembly of ribosomes, as well as in the maintenance and structural integrity of the nucleolus. NSUN6 ( NOL1/NOP2/Sun domain family member 6), also known as NOPD1 (NOL1/NOP2/Sun and PUA domain-containing protein 1), is a 469 amino acid protein that belongs to the methyltransferase superfamily. NSUN6 contains 1 PUA domain and may have S-adenosyl-L-methionine-dependent methyl-transferase activity. The gene encoding NSUN6 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie-tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
Alternative Name:
Putative methyltransferase NSUN6, NOL1/NOP2/Sun and PUA domain-containing protein 1, NOL1/NOP2/Sun domain family member 6, NSUN6, NOPD1
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: NSUN6 polyclonal antibody detects endogenous levels of NSUN6 protein.
Immunogen:
Recombinant full length Human NSUN6.
MW: ~ 52kDa
Swis Prot.: Q8TEA1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The nucleolus consists of a number of specific proteins that play a critical role in the assembly of ribosomes, as well as in the maintenance and structural integrity of the nucleolus. NSUN6 ( NOL1/NOP2/Sun domain family member 6), also known as NOPD1 (NOL1/NOP2/Sun and PUA domain-containing protein 1), is a 469 amino acid protein that belongs to the methyltransferase superfamily. NSUN6 contains 1 PUA domain and may have S-adenosyl-L-methionine-dependent methyl-transferase activity. The gene encoding NSUN6 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie-tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
Alternative Name:
Putative methyltransferase NSUN6, NOL1/NOP2/Sun and PUA domain-containing protein 1, NOL1/NOP2/Sun domain family member 6, NSUN6, NOPD1
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: NSUN6 polyclonal antibody detects endogenous levels of NSUN6 protein.
Immunogen:
Recombinant full length Human NSUN6.
MW: ~ 52kDa
Swis Prot.: Q8TEA1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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