NT-4 human active recombinant protein
€295.00
In stock
SKU
600332
Protein Family: Cytokines
Pathway and Disease: Nervous and Sensory Systems, Signal Transduction
Alternate Names: NT-4/5, Neurotrophin 5, NT-5, Neurotrophic FactorDescription:
Neurotrophin-4 (NT-4) is an important member of the nerve growth factor (NGF) family of proteins along with NT-3, BDNF and NGF. Neurotrophins act in a paracrine and/or autocine manner to control neuronal numbers and dendrite outgrowth. These functions are thought to be communicated by TrkB, a receptor tryrosine kinase that NT-4 shares with BDNF. Human NT-4 is produced in E.coli. Recombinant human NT-4 is a non-glycosylated, non-covalently linked homodimer, containing two 131 amino acid chains, with a total molecular weight of 28.1 kDa.
Source: E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.
Applications: E, WB
Application Notes:
The activity is determined by the dose-dependent proliferation of C6 cells and is typically in the range of 1-5 ug/mL. Specific activity: 1 x 10e3 units/mg
Accession No.: P34130
MW: 28100 Da
Sequence:
MGVSETAPAS RRGELAVCDA VSGWVTDRRT AVDLRGREVE VLGEVPAAGG SPLRQYFFET RCKADNAEEG GPGAGGGGCR GVDRRHWVSE CKAKQSYVRA LTADAQGRVG WRWIRIDTAC VCTLLSRTGR A
Purity:
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Format:
Each vial contains 10 ug of lyophilized protein. Reconstitute with 0.1 ml sterile deionized water for a final concentration of 0.1 mg/ml.
Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
Pathway and Disease: Nervous and Sensory Systems, Signal Transduction
Alternate Names: NT-4/5, Neurotrophin 5, NT-5, Neurotrophic FactorDescription:
Neurotrophin-4 (NT-4) is an important member of the nerve growth factor (NGF) family of proteins along with NT-3, BDNF and NGF. Neurotrophins act in a paracrine and/or autocine manner to control neuronal numbers and dendrite outgrowth. These functions are thought to be communicated by TrkB, a receptor tryrosine kinase that NT-4 shares with BDNF. Human NT-4 is produced in E.coli. Recombinant human NT-4 is a non-glycosylated, non-covalently linked homodimer, containing two 131 amino acid chains, with a total molecular weight of 28.1 kDa.
Source: E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.
Applications: E, WB
Application Notes:
The activity is determined by the dose-dependent proliferation of C6 cells and is typically in the range of 1-5 ug/mL. Specific activity: 1 x 10e3 units/mg
Accession No.: P34130
MW: 28100 Da
Sequence:
MGVSETAPAS RRGELAVCDA VSGWVTDRRT AVDLRGREVE VLGEVPAAGG SPLRQYFFET RCKADNAEEG GPGAGGGGCR GVDRRHWVSE CKAKQSYVRA LTADAQGRVG WRWIRIDTAC VCTLLSRTGR A
Purity:
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Format:
Each vial contains 10 ug of lyophilized protein. Reconstitute with 0.1 ml sterile deionized water for a final concentration of 0.1 mg/ml.
Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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