NTP polyclonal, anti-human, mouse, rat

Protein Family: Cytoskeleton Proteins

Pathway and Disease: Neurodegenerative Disorders, Cell Growth and Death

Description:
Neuronal thread protein (NTP) is composed almost entirely of Alu repeat sequences, and the mRNA encoding this protein is expressed in neurons. Overexpression of NTP is associated with neurofibrillary tangles of Alzheimer's disease. Both CSF and urine levels of NTP have been investigated as a biochemical marker of Alzheimer's disease. In vitro studies have also demonstrated that abnormal expression of this protein promotes neuritic sprouting and cell death, which is associated with dementia in Alzheimer's disease.

Alternate Names: NTP, Neural thread protein, Neuronal thread protein, AD7C-NTP

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: AF010144

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human NTP.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.