NTRK1 Polyclonal Antibody

Background:
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

Research Area: Cancer, Neuroscience

Synonyms:
gp140trk, High affinity nerve growth factor receptor, High affinity nerve growth factor receptor precursor, MTC, Neurotrophic tyrosine kinase receptor type 1, NTRK1, NTRK1, Oncogene TRK, p14-TrkA, p140 TrkA, p140-TrkA, Slow nerve growth, Trk A, TRK, Trk-A, TRK1, TRK1-transforming tyrosine kinase protein, Tropomyosin-related kinase A, Tyrosine kinase receptor A, Tyrosine kinase receptor

Immunogen: Synthetic peptide of human NTRK1

Swissprot: P04629
Gene Accession: NP_002520.2

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.8 mg/mL
Dilution: IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-20539/sc-20537/sc-118/sc-14024/sc-11