NTRK3 polyclonal, anti-human

NTRK3 polyclonal, anti-human

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In stock
SKU
AC-AP7688d
Catalog Number: AC-AP7688d
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB16731
Applications: WB, IHC-P
Datasheet

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Background:
NTRK3, a member of the insuline receptor subfamily of Tyr protein kinases, is a receptor for neurotrophin-3 (NT-3). Known substrates for the NTRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. NTRK3 is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.

Other Names:
NT-3 growth factor receptor, GP145-TrkC, Trk-C, Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase, NTRK3, TRKC

Target/Specificity:
This NTRK3 antibody is generated from rabbits immunized with a his tag recombinant protein of human NTRK3.

Antigen Type: Recombinant Protein

Gene Name: NTRK3
Gene ID: 4916
Primary Accession: Q16288
NCBI Accession: NP_001012338.1;NP_002521.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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