NTRK3 polyclonal, anti-human, mouse

Background:
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.

Synonyms: GP145-TrkC, TRKC, gp145(trkC)

Cellular Location: Membrane Single-pass type I membrane protein

Immunogen:
Recombinant protein of human NTRK3

Gene Symbol: NTRK3

Gene ID: 4916

Swiss prot: Q16288

Calculated MW: 94kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.