Nucleostemin polyclonal, anti-human

Background:
The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene.

Alternative Name:
NNP47, GNL3, E2IG3, NS, C77032, E2 induced gene 3 protein, E2-induced gene 3 protein, E2IG3, Estradiol induced nucleotide binding protein, GNL3, GNL3, Guanine nucleotide binding protein like 3 (nucleolar), Guanine nucleotide binding protein like 3, Guanine nucleotide-binding protein-like 3, MGC800, NNP47, Novel nucleolar protein 47, NS, Nucleolar GTP binding protein 3, Nucleolar GTP-binding protein 3, Nucleostemin, Putative nucleotide binding protein estradiol induced,

Application Dilution:
WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Specificity: Nucleostemin polyclonal antibody detects endogenous levels of Nucleostemin protein.

Immunogen:
Recombinant protein corresponding to the C-terminus of human Nucleostemin.

MW: 62 kDa

Swiss-Prot: Q9BVP2(Human)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.