NUDT2 polyclonal (Center), anti-human
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In stock
SKU
AC-AP16121c
Catalog Number: AC-AP16121c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB35251
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB35251
Applications: WB
Datasheet
Request Information
Background:
This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and three transcript variants, all encoding the same protein, have been identified.
Other Names:
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical], Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase, Ap4A hydrolase, Ap4Aase, Diadenosine tetraphosphatase, Nucleoside diphosphate-linked moiety X motif 2, Nudix motif 2, NUDT2, APAH1
Target/Specificity:
This NUDT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-90 amino acids from the Central region of human NUDT2.
Antigen Region:
62-90
Antigen Type: Synthetic Peptide
Gene Name: NUDT2
Gene ID: 318
Primary Accession: P50583
NCBI Accession: NP_001152.1;NP_001231319.1;NP_671701.1;NP_671702.1
Other Accession: NP_671702.1;NP_671701.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and three transcript variants, all encoding the same protein, have been identified.
Other Names:
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical], Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase, Ap4A hydrolase, Ap4Aase, Diadenosine tetraphosphatase, Nucleoside diphosphate-linked moiety X motif 2, Nudix motif 2, NUDT2, APAH1
Target/Specificity:
This NUDT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-90 amino acids from the Central region of human NUDT2.
Antigen Region:
62-90
Antigen Type: Synthetic Peptide
Gene Name: NUDT2
Gene ID: 318
Primary Accession: P50583
NCBI Accession: NP_001152.1;NP_001231319.1;NP_671701.1;NP_671702.1
Other Accession: NP_671702.1;NP_671701.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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