NUMA1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants.

Synonyms: NMP-22, NUMA

Cellular Location: Chromosome Cytoplasm Nucleus matrix cytoskeleton spindle pole

Immunogen:
Recombinant protein of human NUMA1

Gene Symbol: NUMA1

Gene ID: 4926

Swiss prot: Q14980

Calculated MW: 238kDa

Recommended dilution:
WB 1:200-1000, IHC 1:50-100, IF 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.