NUMB monoclonal, anti-human, mouse, rat
€455.00
In stock
SKU
AC-ABO13515
Catalog Number: AC-ABO13515
Size: 100 µl
Isotype: Rabbit IgG
Applications: WB
Datasheet
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Size: 100 µl
Isotype: Rabbit IgG
Applications: WB
Datasheet
Request Information
Description: Anti-NUMB Rabbit Monoclonal Antibody . Tested in WB application. This antibody reacts with Human, Mouse, Rat.
Protein Function:
Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.
Other Names: Protein numb homolog, h-Numb, Protein S171, NUMB (HGNC:8060)
Clone Name(s):
Clone: AOGI-14
Subcellular Localization: Membrane; Peripheral membrane protein.
Gene ID: 8650
Immunogen: A synthesized peptide derived from human NUMB
Calculated MW: 70804
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Protein Function:
Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.
Other Names: Protein numb homolog, h-Numb, Protein S171, NUMB (HGNC:8060)
Clone Name(s):
Clone: AOGI-14
Subcellular Localization: Membrane; Peripheral membrane protein.
Gene ID: 8650
Immunogen: A synthesized peptide derived from human NUMB
Calculated MW: 70804
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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