NUMB polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants.

Synonyms: C14orf41, S171, c14_5527

Cellular Location: Membrane Peripheral membrane protein

Immunogen:
Recombinant protein of human NUMB

Gene Symbol: NUMB

Gene ID: 8650

Swiss prot: P49757

Calculated MW: 71kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.