NUMB Polyclonal Antibody

Background:
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Neuroscience, Stem Cells

Synonyms:
NUMB, C14orf41, S171, c14_5527

Immunogen: Recombinant fusion protein of human NUMB (NP_003735.3).

Swissprot: P49757
Gene ID: 8650

Calculated MW: 37 kDa/48-70 kDa
Observed MW: 71 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.