NUP88 Blocking Peptide (Center)

Background:
The nuclear pore complex is a massive structure thatextends across the nuclear envelope, forming a gateway thatregulates the flow of macromolecules between the nucleus and thecytoplasm. Nucleoporins, a family of 50 to 100 proteins, are themain components of the nuclear pore complex in eukaryotic cells.The protein encoded by this gene belongs to the nucleoporin familyand is associated with the oncogenic nucleoporin CAN/Nup214 in adynamic subcomplex. This protein is also overexpressed in a largenumber of malignant neoplasms and precancerous dysplasias.

Other Names:
Nuclear pore complex protein Nup88, 88 kDa nucleoporin, Nucleoporin Nup88, NUP88

Target/Specificity:
The synthetic peptide sequence is selected from aa 344-356 of HUMAN NUP88

Gene Name: NUP88

Gene ID: 4927
Primary Accession: Q99567
Other Accession: NP_002523.2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.