NUP93 Polyclonal Antibody

Background:
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene encodes a nucleoporin protein that localizes both to the basket of the pore and to the nuclear entry of the central gated channel of the pore. The encoded protein is a target of caspase cysteine proteases that play a central role in programmed cell death by apoptosis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction, Tags and Cell Markers

Synonyms:
NUP93, NIC96, NPHS12

Immunogen: Recombinant fusion protein of human NUP93 (NP_055484.3).

Swissprot: Q8N1F7
Gene ID: 9688

Calculated MW: 79 kDa/93 kDa
Observed MW: 93 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.