NXF1 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP14539a
Background:
This gene is one member of a family of nuclear RNA exportfactor genes. Common domain features of this family are anoncanonical RNP-type RNA-binding domain (RBD), 4 leucine-richrepeats (LRRs), a nuclear transport factor 2 (NTF2)-like domainthat allows heterodimerization with NTF2-related export protein-1(NXT1), and a ubiquitin-associated domain that mediatesinteractions with nucleoporins. The LRRs and NTF2-like domains arerequired for export activity. Alternative splicing seems to be acommon mechanism in this gene family. The encoded protein of thisgene shuttles between the nucleus and the cytoplasm and binds invivo to poly(A)+ RNA. It is the vertebrate homologue of the yeastprotein Mex67p. The encoded protein overcomes the mRNA export blockcaused by the presence of saturating amounts of CTE (constitutivetransport element) RNA of type D retroviruses. Alternative splicingresults in multiple transcript variants.
Other Names:
Nuclear RNA export factor 1, Tip-associated protein, Tip-associating protein, mRNA export factor TAP, NXF1, TAP
Gene Name: NXF1
Gene ID: 10482
Primary Accession: Q9UBU9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene is one member of a family of nuclear RNA exportfactor genes. Common domain features of this family are anoncanonical RNP-type RNA-binding domain (RBD), 4 leucine-richrepeats (LRRs), a nuclear transport factor 2 (NTF2)-like domainthat allows heterodimerization with NTF2-related export protein-1(NXT1), and a ubiquitin-associated domain that mediatesinteractions with nucleoporins. The LRRs and NTF2-like domains arerequired for export activity. Alternative splicing seems to be acommon mechanism in this gene family. The encoded protein of thisgene shuttles between the nucleus and the cytoplasm and binds invivo to poly(A)+ RNA. It is the vertebrate homologue of the yeastprotein Mex67p. The encoded protein overcomes the mRNA export blockcaused by the presence of saturating amounts of CTE (constitutivetransport element) RNA of type D retroviruses. Alternative splicingresults in multiple transcript variants.
Other Names:
Nuclear RNA export factor 1, Tip-associated protein, Tip-associating protein, mRNA export factor TAP, NXF1, TAP
Gene Name: NXF1
Gene ID: 10482
Primary Accession: Q9UBU9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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