NXT1 Blocking Peptide (C-term)

Background:
The protein encoded by this gene is located in the nuclearenvelope. It has protein similarity to nuclear transport factor 2.This protein functions as a nuclear export factor in both RAN(Ras-related nuclear protein)- and CRM1 (required for chromosomeregion maintenance)-dependent pathways. It is found to stimulatethe export of U1 snRNA in RAN- and CRM1-dependent pathways and theexport of tRNA and mRNA in a CRM1-independent pathway. The encodedprotein heterodimerizes with Tap protein and may regulate theability of Tap protein to mediate nuclear mRNA export. The use ofalternate polyadenylation sites has been found for this gene.

Other Names:
NTF2-related export protein 1, Protein p15, NXT1

Target/Specificity:
The synthetic peptide sequence is selected from aa 100-111 of HUMAN NXT1

Gene Name: NXT1

Gene ID: 29107
Primary Accession: Q9UKK6
Other Accession: Q9QZV9; Q2KIW0; NP_037380.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.