NXT1 cDNA
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In stock
SKU
ATGD0151
Description
NXT1 encoded by this gene is located in the nuclear envelope. NXT1 has protein similarity to nuclear transport factor 2. NXT1 functions as a nuclear export factor in both RAN (Ras-related nuclear protein) - and CRM1 (required for chromosome region maintenance) -dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for NXT1.Alternative Names
MTR2, P15Concentration
LyophilizedStorage: Store the plasmid at -20C.
NXT1 encoded by this gene is located in the nuclear envelope. NXT1 has protein similarity to nuclear transport factor 2. NXT1 functions as a nuclear export factor in both RAN (Ras-related nuclear protein) - and CRM1 (required for chromosome region maintenance) -dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for NXT1.Alternative Names
MTR2, P15Concentration
LyophilizedStorage: Store the plasmid at -20C.
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