NYX polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS71450
Background:
The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB.
Alternative Name:
CLRP, NBM1, CSNB1, CSNB4, CSNB1A,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: NYX polyclonal antibody detects endogenous levels of NYX protein.
Immunogen:
Recombinant protein of human NYX.
MW: ~ 52 kDa
Swis Prot.: Q9GZU5
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB.
Alternative Name:
CLRP, NBM1, CSNB1, CSNB4, CSNB1A,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: NYX polyclonal antibody detects endogenous levels of NYX protein.
Immunogen:
Recombinant protein of human NYX.
MW: ~ 52 kDa
Swis Prot.: Q9GZU5
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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