OAS1 polyclonal, anti-human, mouse, rat, monkey, pig

Protein Family: Enzymes, Protein Kinases

Pathway and Disease: Cell Growth and Death, Development and Behavior, Immune System

Description:
OAS1 is involved in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS1 binds double-stranded RNA and polymerizes ATP into PPP(A2'P5'A)N oligomers, which activate the latent Rnase L to cleaves single-stranded RNAs.

Alternate Names: 2'-5'-oligoadenylate synthetase 1, 2-5' oligo(A) synthetase 1, 2-5A synthetase 1, p46/p42 OAS, E18/E16, OAS1, OIAS

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500

Accession No.: P00973, NP_002525

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human OAS1.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.