OAS2 Polyclonal Antibody
€0.00
In stock
SKU
ELK-ES4266
Catalog Number: ELK-ES4266
Reactivity: Human
Applications: WB, IHC-p, ELISA
Information
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Reactivity: Human
Applications: WB, IHC-p, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Background:
2'-5'-oligoadenylate synthetase 2(OAS2) Homo sapiens This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],
Alternative Names:
OAS2, 2'-5'-oligoadenylate synthase 2, (2-5')oligo(A) synthase 2, 2-5A synthase 2, p69 OAS / p71 OAS, p69OAS / p71OAS
Immunogen: The antiserum was produced against synthesized peptide derived from the N-terminal region of human OAS2. AA range:61-110
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 82
GeneID: OAS2
Storage: -20°C/1 year
NOTE: For Research Use Only
2'-5'-oligoadenylate synthetase 2(OAS2) Homo sapiens This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],
Alternative Names:
OAS2, 2'-5'-oligoadenylate synthase 2, (2-5')oligo(A) synthase 2, 2-5A synthase 2, p69 OAS / p71 OAS, p69OAS / p71OAS
Immunogen: The antiserum was produced against synthesized peptide derived from the N-terminal region of human OAS2. AA range:61-110
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 82
GeneID: OAS2
Storage: -20°C/1 year
NOTE: For Research Use Only
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