OBCAM polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS72029
Background:
This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily of proteins. The encoded preprotein is proteolytically processed to generate the mature protein. This protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Alternative Name:
Opioid-binding protein/cell adhesion molecule, OBCAM, OPCML, Opioid-binding cell adhesion molecule, IgLON family member 1, IGLON1, OBCAM, OPCML
Application Dilution: WB: 1:1000 - 1:2000
Specificity: OBCAM polyclonal antibody detects endogenous levels of OBCAM protein.
Immunogen:
Recombinant protein of human OPCML
MW: 36kDa
Swis Prot.: Q14982
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily of proteins. The encoded preprotein is proteolytically processed to generate the mature protein. This protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Alternative Name:
Opioid-binding protein/cell adhesion molecule, OBCAM, OPCML, Opioid-binding cell adhesion molecule, IgLON family member 1, IGLON1, OBCAM, OPCML
Application Dilution: WB: 1:1000 - 1:2000
Specificity: OBCAM polyclonal antibody detects endogenous levels of OBCAM protein.
Immunogen:
Recombinant protein of human OPCML
MW: 36kDa
Swis Prot.: Q14982
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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