Ochratoxin A monoclonal, anti-
€0.00
In stock
SKU
BDA1022
Background:
Ochratoxins are a group of mycotoxins produced by some Aspergillus species and some Penicillium species, especially P. verrucosum and P. carbonarius. Ochratoxin A is the most prevalent and relevant fungal toxin of this group, while ochratoxins B and C are of lesser importance. Ochratoxin A (OTA), a toxin produced by several species of Aspergillus and Penicillium, is one of the most abundant food-contaminating mycotoxins. There were high levels of OTA contaminations in wheat in the areas with high incidence of esophageal cancer in north China. This finding suggests that exposure to low levels of OTA may be a critical etiological factor for esophageal cancer in these areas. It could induce DNA damage, G2 arrest and apoptosis in Het-1A cells, which may be involved in the esophageal toxicity of OTA. OTA in red chili peppers may be associated with the development of gallbladder cancer.
Recommended Application:
ELISA; (1:100000)
Product Form: Liquid
Purification & Buffer: Protein A or G purified and supplied in 0.01 M PBS (pH7.4)
Purity: >95% by HPLC & SDS-PAGE
Storage Instruction:
Aliquot and store at -20℃ for 2 years. Avoid repeated freeze and thaw cycles.
Ochratoxins are a group of mycotoxins produced by some Aspergillus species and some Penicillium species, especially P. verrucosum and P. carbonarius. Ochratoxin A is the most prevalent and relevant fungal toxin of this group, while ochratoxins B and C are of lesser importance. Ochratoxin A (OTA), a toxin produced by several species of Aspergillus and Penicillium, is one of the most abundant food-contaminating mycotoxins. There were high levels of OTA contaminations in wheat in the areas with high incidence of esophageal cancer in north China. This finding suggests that exposure to low levels of OTA may be a critical etiological factor for esophageal cancer in these areas. It could induce DNA damage, G2 arrest and apoptosis in Het-1A cells, which may be involved in the esophageal toxicity of OTA. OTA in red chili peppers may be associated with the development of gallbladder cancer.
Recommended Application:
ELISA; (1:100000)
Product Form: Liquid
Purification & Buffer: Protein A or G purified and supplied in 0.01 M PBS (pH7.4)
Purity: >95% by HPLC & SDS-PAGE
Storage Instruction:
Aliquot and store at -20℃ for 2 years. Avoid repeated freeze and thaw cycles.
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