OCLN polyclonal, anti-human, mouse, rat

Background:
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.

Synonyms: BLCPMG, PPP1R115

Cellular Location: Cell junction Membrane Multi-pass membrane protein tight junction

Immunogen:
Recombinant protein of human OCLN

Gene Symbol: OCLN

Gene ID: 100506658

Swiss prot: Q16625

Calculated MW: 59kDa

Recommended dilution:
WB 1:1000-2000, IHC 1:50-200, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.