OCLN Polyclonal Antibody

Background:
Occludin is an integral membrane protein located at the tight junction. It is a tetraspanin protein with four transmembrane domains, intracellular N and C termini and two extracellular loops. Occludin plays a role in the formation and regulation of the tight junction paracellular permeability barrier. Occludin can exist in different isoforms, owing to modifications at the posttranscriptional and posttranslational levels .

Research Area: Cancer, Signal Transduction

Synonyms:
BLCPMG, FLJ08163, FLJ18079, FLJ77961, FLJ94056, MGC34277, Occludin, Ocln, OCLN, Phosphatase 1 regulatory subunit 115, PPP1R115, PTORCH1, Tight junction protein occludin

Immunogen: Recombinant protein corresponding to Mouse occludin

Swissprot: Q61146,Q6P6T5

Calculated MW: 59 kDa
Observed MW: 60 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 0.56 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Citation(s):
https://pubmed.ncbi.nlm.nih.gov/32439558/
https://pubmed.ncbi.nlm.nih.gov/32651640/