OCRL polyclonal, anti-human, mouse, rat

Background:
This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.

Synonyms: INPP5F, LOCR, NPHL2, OCRL-1, OCRL1

Cellular Location: Cell projection Cytoplasmic vesicle Early endosome membrane Endosome Golgi apparatus Membrane cilium clathrin-coated pit phagosome membrane photoreceptor outer segment trans-Golgi network

Immunogen:
Recombinant protein of human OCRL

Gene Symbol: OCRL

Gene ID: 4952

Swiss prot: Q01968

Calculated MW: 104kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.