DHRS2 polyclonal, anti-human, mouse
€470.00
In stock
SKU
AC-AP69531
Catalog Number: AC-AP51440
Size: 100 µl
Host: Rabbit
Applications: WB, ICC, IHC-P, E
Datasheet
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Size: 100 µl
Host: Rabbit
Applications: WB, ICC, IHC-P, E
Datasheet
Request Information
Background:
Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2- propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.
Other Names:
DHRS2; Dehydrogenase/reductase SDR family member 2; Dicarbonyl reductase HEP27; Protein D
Antigen Type: synthetic peptide
Antigen Type: DHRS2 (HGNC:18349)
Gene ID: 10202
Primary Accession: Q13268
Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2- propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.
Other Names:
DHRS2; Dehydrogenase/reductase SDR family member 2; Dicarbonyl reductase HEP27; Protein D
Antigen Type: synthetic peptide
Antigen Type: DHRS2 (HGNC:18349)
Gene ID: 10202
Primary Accession: Q13268
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