OGCP polyclonal antibody, anti-human, mouse, rat

Background:
Inner membrane mitochondrial proteins are responsible for the transport of metabolites across the mitochondrial membrane. SLC25A11 (Solute carrier family 25 member 11), also known as Mitochondrial 2-oxoglutarate/malate carrier protein, is a 314 amino acid multi-pass transmembrane protein belonging to the mitochondrial carrier protein family. As an oxoglutarate/malate carrier, SLC25A11 transports 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for dicarboxylic acids and malate. SLC25A11 also participates in other important metabolic processes, such as the oxoglutarate/isocitrate shuttle and the malate-aspartate shuttle, as well as in nitrogen metabolism and in gluconeogenesis from lactate. SLC25A11 contains 3 solcar repeats, which is typical of substrate carrier proteins involved in energy transfer.

Research Area: Tags & Cell Markers

Synonyms: SLC25A11, SLC20A4, Mitochondrial 2-oxoglutarate/malate carrier protein, OGCP, Solute carrier family 25 member 11

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year