OGDH Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13442b
Background:
This gene encodes one subunit of the 2-oxoglutaratedehydrogenase complex. This complex catalyzes the overallconversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoAand CO(2) during the Krebs cycle. The protein is located in themitochondrial matrix and uses thiamine pyrophosphate as a cofactor.A congenital deficiency in 2-oxoglutarate dehydrogenase activity isbelieved to lead to hypotonia, metabolic acidosis, andhyperlactatemia. Alternative splicing results in multipletranscript variants encoding distinct isoforms.
Other Names:
2-oxoglutarate dehydrogenase, mitochondrial, 2-oxoglutarate dehydrogenase complex component E1, OGDC-E1, Alpha-ketoglutarate dehydrogenase, OGDH
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13442b was selected from the C-term region of OGDH. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: OGDH (HGNC:8124)
Gene ID: 4967
Primary Accession: Q02218
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes one subunit of the 2-oxoglutaratedehydrogenase complex. This complex catalyzes the overallconversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoAand CO(2) during the Krebs cycle. The protein is located in themitochondrial matrix and uses thiamine pyrophosphate as a cofactor.A congenital deficiency in 2-oxoglutarate dehydrogenase activity isbelieved to lead to hypotonia, metabolic acidosis, andhyperlactatemia. Alternative splicing results in multipletranscript variants encoding distinct isoforms.
Other Names:
2-oxoglutarate dehydrogenase, mitochondrial, 2-oxoglutarate dehydrogenase complex component E1, OGDC-E1, Alpha-ketoglutarate dehydrogenase, OGDH
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13442b was selected from the C-term region of OGDH. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: OGDH (HGNC:8124)
Gene ID: 4967
Primary Accession: Q02218
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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