OGN polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8348
Background:
The small leucine-rich proteoglycan (SLRP) family of proteins contains various proteins such as Decorin, Biglycan, Fibromodulin, Keratocan, Lumican, Osteoadherin and Osteoglycin. These proteins all have similar functions as they all mediate extracellular matrix organization and act as binding partners of TGFβ. Osteoglycin, which also may be designated osteoinductive factor (OIF), is a secreted protein detected in bone tissues. Osteoglycin induces the formation of bone in conjunction with either TFGβ1 or TGFβ2. The precursor form of the OGN gene product, designated Mimecan, is subject to in situ proteolytic cleavage to yield the mature Osteoglycin.
Alternative Name:
Mimecan, Osteoglycin, Osteoinductive factor, OIF, OGN, OIF, SLRR3A
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: OGN polyclonal antibody detects endogenous levels of OGN protein.
Immunogen:
Recombinant full length Human OGN.
MW: ~ 34 kDa
Swis Prot.: P20774
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The small leucine-rich proteoglycan (SLRP) family of proteins contains various proteins such as Decorin, Biglycan, Fibromodulin, Keratocan, Lumican, Osteoadherin and Osteoglycin. These proteins all have similar functions as they all mediate extracellular matrix organization and act as binding partners of TGFβ. Osteoglycin, which also may be designated osteoinductive factor (OIF), is a secreted protein detected in bone tissues. Osteoglycin induces the formation of bone in conjunction with either TFGβ1 or TGFβ2. The precursor form of the OGN gene product, designated Mimecan, is subject to in situ proteolytic cleavage to yield the mature Osteoglycin.
Alternative Name:
Mimecan, Osteoglycin, Osteoinductive factor, OIF, OGN, OIF, SLRR3A
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: OGN polyclonal antibody detects endogenous levels of OGN protein.
Immunogen:
Recombinant full length Human OGN.
MW: ~ 34 kDa
Swis Prot.: P20774
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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