OGT polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7343
Background:
This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alternative Name:
GlcNAc transferase, HRNT1, MGC22921, O GlcNAc, O GlcNAc transferase p110 subunit, O GlcNAc transferase subunit p110, O linked N acetylglucosamine (GlcNAc) transferase (UDP N acetylglucosamine:polypeptide N acetylglucosaminyl transferase), O linked N acetylglucosamine (GlcNAc) transferase, O linked N acetylglucosamine transferase 110 kDa subunit, O-GlcNAc transferase subunit p110, O-linked N-acetylglucosamine transferase 110 kDa subunit, OGT, OGT1_HUMAN, UDP N acetylglucosamine peptide N acetylglucosaminyltransferase 110 kDa subunit, UDP N acetylglucosamine peptide N acetylglucosaminyltransferase GlcNAc transferase, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase, Uridinediphospho N acetylglucosamine:polypeptide beta N acetylglucosaminyl transferase,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: OGT polyclonal antibody detects endogenous levels of OGT protein.
Immunogen:
Recombinant full length Human OGT.
MW: ~117 kDa
Swis Prot.: O15294
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alternative Name:
GlcNAc transferase, HRNT1, MGC22921, O GlcNAc, O GlcNAc transferase p110 subunit, O GlcNAc transferase subunit p110, O linked N acetylglucosamine (GlcNAc) transferase (UDP N acetylglucosamine:polypeptide N acetylglucosaminyl transferase), O linked N acetylglucosamine (GlcNAc) transferase, O linked N acetylglucosamine transferase 110 kDa subunit, O-GlcNAc transferase subunit p110, O-linked N-acetylglucosamine transferase 110 kDa subunit, OGT, OGT1_HUMAN, UDP N acetylglucosamine peptide N acetylglucosaminyltransferase 110 kDa subunit, UDP N acetylglucosamine peptide N acetylglucosaminyltransferase GlcNAc transferase, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase, Uridinediphospho N acetylglucosamine:polypeptide beta N acetylglucosaminyl transferase,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: OGT polyclonal antibody detects endogenous levels of OGT protein.
Immunogen:
Recombinant full length Human OGT.
MW: ~117 kDa
Swis Prot.: O15294
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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