OGT Polyclonal Antibody

Background:
This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Research Area: Cancer, Neuroscience, Signal Transduction

Synonyms:
OGT, HINCUT-1, HRNT1, O-GLCNAC, MRX106, OGT1

Immunogen: Recombinant fusion protein of human OGT (NP_858059.1).

Swissprot: O15294
Gene ID: 8473

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.