OLFM1 polyclonal, anti-human, mouse

OLFM1 polyclonal, anti-human, mouse

€388.00
In stock
SKU
BS6004
Catalog Number: BS6004
Size: 50 ul, 100 ul
Isotype: rabbit IgG
Applications: WB

Datasheet
Background:
The Olfactomedin family comprises a diverse group of secreted glycoproteins, which includes OLFM1 (Noelin-1), OLFM2 (Noelin-2), OLFM3 (Noelin-3), OLFM4 (Noelin-4), tiarin, pancortin, gliomedin and mycocilin. These proteins are implicated in the development of the nervous system. Specifically, OLFM1 and OLFM2 expression is observed in the neural plate and neural crest, as well as in the cranial ganglia in mouse at E8-10, and later in brain tissue and in the zone of polarizing activity in the limb. Overexpression of OLFM1 causes an excess of neural crest emigrations and prolonged neural crest production. OLFM2 participates in the regulation of the development of the anterior nervous system. An Arg144Gln mutation in OLFM2 has been implicated as a possible cause for open-angle glaucoma (OAG).

Alternative Name:
AMY, NEUROBLASTOMA PROTEIN, Neuronal olfactomedin-related ER localized protein, Noe1, NOE1, Noel, Noel1, Noelin, Noelin1, OlfA, Olfactomedin 1, Olfactomedin-1, Olfm1, Pancortin 1, Pancortin,

Application Dilution: WB: 1:500 - 1:2000

Specificity: OLFM1 polyclonal antibody detects endogenous levels of OLFM1 protein.

Immunogen:
Recombinant full length Human OLFM1.

MW: ~ 55 kDa

Swis Prot.: Q99784

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.
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