OLIG2 (clone 1G11), anti-human
€0.00
In stock
SKU
BT-MCA4423
Catalog Number: BT-MCA4423
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s): IHC, ICC
Datasheet
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Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s): IHC, ICC
Datasheet
Request Information
Background:
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.
Research Area: Epigenetics and nuclear signaling, Neuroscience, Stem cells
Synonyms: BHLHB1, OLIGO2, RACK17, PRKCBP2, bHLHe19, OLIG2
Immunogen: Purified recombinant fragment of human OLIG2 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage:
4°C|-20°C for long term storage
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.
Research Area: Epigenetics and nuclear signaling, Neuroscience, Stem cells
Synonyms: BHLHB1, OLIGO2, RACK17, PRKCBP2, bHLHe19, OLIG2
Immunogen: Purified recombinant fragment of human OLIG2 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage:
4°C|-20°C for long term storage
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