Olig2 polyclonal, anti-human, mouse, rat
€510.00
In stock
SKU
253199
Catalog Nr.: 253199
Size: 0.1 ml
Isotype: Rabbit Ig
Applications: E, WB, ICC, IHC, IP
Datasheet
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Size: 0.1 ml
Isotype: Rabbit Ig
Applications: E, WB, ICC, IHC, IP
Datasheet
Request Information
Protein Family: Transcription Factors
Pathway and Disease: Nervous and Sensory Systems
Description:
Olig2 is a transcription factor which is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Olig2 is expressed in the ventral spinal cord as early as 9.5 dpc and scattered in the mantle zone, likely corresponding to oligodendrocyte progenitors migrating out from their site of origin. From 10.5 through 14.5 dpc, olig2 is expressed in numerous cells in the ventricular and subventricular zones of the lateral and medial ganglionic eminences, suggesting that expression might not be limited to the oligodendrocytic lineage. Olig2 has further been shown to be critical in the proliferation of malignant glioma in brain tumors.
Alternate Names: Oligodendrocyte transcription factor 2, Oligo2, Olig2
Application Notes: E: 1:1,000-1:5,000; WB: 1:3,000; IHC: 1:1,000; ICC: 1:1,000; IP: 1:500-1:1,000
Accession No.: Q9EQW6
Antigen: Recombinant mouse Olig2.
Format: Each vial contains 0.1 ml IgG in Tris pH8.0, 100mM glycine with 0.065% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Nervous and Sensory Systems
Description:
Olig2 is a transcription factor which is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Olig2 is expressed in the ventral spinal cord as early as 9.5 dpc and scattered in the mantle zone, likely corresponding to oligodendrocyte progenitors migrating out from their site of origin. From 10.5 through 14.5 dpc, olig2 is expressed in numerous cells in the ventricular and subventricular zones of the lateral and medial ganglionic eminences, suggesting that expression might not be limited to the oligodendrocytic lineage. Olig2 has further been shown to be critical in the proliferation of malignant glioma in brain tumors.
Alternate Names: Oligodendrocyte transcription factor 2, Oligo2, Olig2
Application Notes: E: 1:1,000-1:5,000; WB: 1:3,000; IHC: 1:1,000; ICC: 1:1,000; IP: 1:500-1:1,000
Accession No.: Q9EQW6
Antigen: Recombinant mouse Olig2.
Format: Each vial contains 0.1 ml IgG in Tris pH8.0, 100mM glycine with 0.065% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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