OLIG2 Polyclonal Antibody

Background:
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome.

Research Area: Neuroscience,Epigenetics and Nuclear Signaling,Stem Cells

Synonyms:
OLIG2, BHLHB1, OLIGO2, PRKCBP2, RACK17, bHLHe19

Immunogen: Recombinant fusion protein of human OLIG2 (NP_005797.1).

Swissprot: Q13516
Gene ID: 10215

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.