OLR1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.

Synonyms: CLEC8A, LOX1, LOXIN, SCARE1, SLOX1

Cellular Location: Cell membrane Lipid-anchor Membrane raft Secreted Single-pass type II membrane protein

Immunogen:
Recombinant protein of human OLR1

Gene Symbol: OLR1

Gene ID: 4973

Swiss prot: P78380

Calculated MW: 31kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.