OLR1 Polyclonal Antibody

Background:
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.

Research Area: Cancer, Cardiovascular, Metabolism

Synonyms:
OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1

Immunogen: A synthetic peptide of human OLR1 (NP_002534.1).

Swissprot: P78380
Gene ID: 4973

Calculated MW: 20 kDa/21 kDa/30 kDa
Observed MW: 31 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:1000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.